BDBM426169 5-(2-(4-Fluorophenyl)-8-(2-oxa-6-azaspiro[3;3]heptan-6-yl)imidazo[1,2-::US10513523, Example 108

SMILES Fc1ccc(cc1)-c1nc2c(nccn2c1-c1ccc2NS(=O)(=O)Cc2c1)N1CC2(COC2)C1

InChI Key InChIKey=AJIJXCKJTYPOOQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426169   

TargetGlutamate receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM426169(US10513523, Example 108 | 5-(2-(4-Fluorophenyl)-8-...)
Affinity DataIC50: 16nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
US Patent