BDBM426259 5-[2-tert-Butyl-7-(6-oxa-2-azaspiro[3;3]heptan-2-yl)pyrazolo[1,5-::US10513523, Example 199

SMILES CC(C)(C)c1nn2c(nccc2c1-c1ccc2NC(=O)Cc2c1)N1CC2(COC2)C1

InChI Key InChIKey=GSJACVVCKLIQSD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426259   

TargetGlutamate receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM426259(US10513523, Example 199 | 5-[2-tert-Butyl-7-(6-oxa...)
Affinity DataIC50: 320nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2020
Entry Details
US Patent