BDBM427174 US10544132, Example 115

SMILES CC[C@@](O)(c1cc2C(=O)N(Cc3ccc(Cl)cc3OCC([O-])=O)[C@](OC)(c2c(F)c1)c1ccc(Cl)cc1)C1(F)CCOCC1

InChI Key InChIKey=JJZSDEJWGNDCRG-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 427174   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 427174BDBM427174(US10544132, Example 115)
Affinity DataIC50: 7.30E+4nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent