BDBM427288 (S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-(fluoromethyl)-[2,4′-bipyridin]-2′-yl)carbamate::US10544120, Example 280

SMILES COC(=O)Nc1cc(ccn1)-c1ccc(OC[C@@](C)(N)CC(C)C)c(CF)n1

InChI Key InChIKey=CNAFHIKHNXQPGG-FQEVSTJZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 427288   

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM427288((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)
Affinity DataIC50:  1.10nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent