BDBM427304 (S)-methyl (4-(5-((2,4 dimethylpentyl)oxy)6-methypyridin-2-yl)pyrimidin-2-yl)carbamate::US10544120, Example 312

SMILES COC(=O)Nc1nccc(n1)-c1ccc(OC[C@@](C)(N)CC(C)C)c(C)n1

InChI Key InChIKey=QHAJPDBDWJDQPA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 427304   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM427304(US10544120, Example 312 | (S)-methyl (4-(5-((2,4 d...)
Affinity DataIC50: 4.90nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent