BDBM427354 (S)-methyl (6-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-(trifluoromethyl)phenyl)pyrimidin-4-yl)carbamate::US10544120, Example 432

SMILES COC(=O)Nc1cc(ncn1)-c1ccc(OC[C@@](C)(N)CC(C)C)c(c1)C(F)(F)F

InChI Key InChIKey=KBZFWOCHVZRANF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 427354   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM427354(US10544120, Example 432 | (S)-methyl (6-(4-((2-ami...)
Affinity DataIC50: 0.700nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
Go to US Patent