BDBM427356 (S)-methyl (4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-methylphenyl)pyrimidin-2-yl)carbamate::US10544120, Example 434

SMILES COC(=O)Nc1nccc(n1)-c1ccc(OC[C@](C)(CC(C)C)NC(=O)OC(C)(C)C)c(C)c1

InChI Key InChIKey=AZWVRHRVDPXEEY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 427356   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM427356(US10544120, Example 434 | (S)-methyl (4-(4-((2-ami...)
Affinity DataIC50: 4.70nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent