BDBM427360 (S)-methyl(6-(6-((2-amino-2,4-dimethylpentyl)oxy)-5-methylpyridin-3-yl)pyrimidin-4-yl)carbamate::US10544120, Example 438

SMILES COC(=O)Nc1cc(ncn1)-c1cnc(OC[C@@](C)(N)CC(C)C)c(C)c1

InChI Key InChIKey=LWCUISZWGAZAMB-IBGZPJMESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 427360   

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM427360((S)-methyl(6-(6-((2-amino-2,4-dimethylpentyl)oxy)-...)
Affinity DataIC50:  6.5nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent