BDBM4275 2-{[4-(methylsulfanyl)phenyl]methylidene}propanedinitrile::Tyrphostin deriv. 5

SMILES [#6]-[#16]-c1ccc(\[#6]=[#6](/C#N)C#N)cc1

InChI Key InChIKey=CWBMWSAMPGILNT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4275   

TargetEpidermal growth factor receptor(Human)
Hebrew University of Jerusalem

LigandPNGBDBM4275(2-{[4-(methylsulfanyl)phenyl]methylidene}propanedi...)
Affinity DataIC50: 6.25E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2005
Entry Details Article
PubMed