BDBM427782 US10544143, Example 215::US10544143, Example 220::US10544143, Example 235::US10730877, Example 235::US11053244, Example 220

SMILES CC(C)c1c([nH]c2ccc(nc12)C1CCC(CC1)NC1COC1)-c1cc(CO)c2ncnn2c1

InChI Key InChIKey=RCFXDLXTECFJHV-UHFFFAOYSA-N

Data  27 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 427782   

TargetToll-like receptor 8(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 6.10nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetToll-like receptor 9(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 929nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/13/2022
Entry Details
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TargetToll-like receptor 8(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 2nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/13/2022
Entry Details
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TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/13/2022
Entry Details
Copy BDB DOIUS Patent

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TargetToll-like receptor 9(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 1.02E+3nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/13/2022
Entry Details
Copy BDB DOIUS Patent

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TargetToll-like receptor 8(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 6.10nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/13/2022
Entry Details
Copy BDB DOIUS Patent

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TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 6.70nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/13/2022
Entry Details
Copy BDB DOIUS Patent

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TargetToll-like receptor 9(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 2.25E+3nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/13/2022
Entry Details
Copy BDB DOIUS Patent

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TargetToll-like receptor 8(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 7.60nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/13/2022
Entry Details
Copy BDB DOIUS Patent

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TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 6nMAssay Description:HEK-Blue -cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducibl...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/13/2022
Entry Details
Copy BDB DOIUS Patent

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TargetToll-like receptor 9(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 929nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/27/2021
Entry Details
Copy BDB DOIUS Patent

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TargetToll-like receptor 8(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 2nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/27/2021
Entry Details
Copy BDB DOIUS Patent

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TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/27/2021
Entry Details
Copy BDB DOIUS Patent

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TargetToll-like receptor 9(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 1.02E+3nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/27/2021
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 6nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/2/2020
Entry Details
Copy BDB DOIUS Patent

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TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 6.70nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/27/2021
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL

TargetToll-like receptor 9(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 2.25E+3nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/27/2021
Entry Details
Copy BDB DOIUS Patent

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TargetToll-like receptor 8(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 7.60nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/27/2021
Entry Details
Copy BDB DOIUS Patent

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TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 6nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/27/2021
Entry Details
Copy BDB DOIUS Patent

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TargetToll-like receptor 9(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 929nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/2/2020
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL

TargetToll-like receptor 8(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 2nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/2/2020
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/2/2020
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL

TargetToll-like receptor 9(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 1.02E+3nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/2/2020
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL

TargetToll-like receptor 8(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 6.10nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/2/2020
Entry Details
Copy BDB DOIUS Patent

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TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 6.70nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/2/2020
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL

TargetToll-like receptor 9(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 2.25E+3nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/2/2020
Entry Details
Copy BDB DOIUS Patent

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TargetToll-like receptor 8(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM427782(US10544143, Example 215 | US10544143, Example 235 ...)Copy SMILESCopy InChI

Affinity DataIC50: 7.60nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/2/2020
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL