BDBM4281 2-[(4-methanesulfinylphenyl)methylidene]propanedinitrile::Tyrphostin deriv. 12::[4-(Methylsulfinyl)Benzylidene]malononitrile

SMILES [#6]S(=O)c1ccc(\[#6]=[#6](/C#N)C#N)cc1

InChI Key InChIKey=MVOSYVAMGLEZRZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4281   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4281(2-[(4-methanesulfinylphenyl)methylidene]propanedin...)
Affinity DataIC50:  1.80E+6nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed