BDBM429536 US10550089, Example 10::US10995072, Example 11

SMILES CCCc1c(F)c(F)ccc1C(O)c1ncc[nH]1

InChI Key

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 429536   

TargetProteinase-activated receptor 2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM429536(US10550089, Example 10 | US10995072, Example 11)
Affinity DataIC50:  1.66E+3nMAssay Description:Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProteinase-activated receptor 2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM429536(US10550089, Example 10 | US10995072, Example 11)
Affinity DataIC50:  5.90E+3nMAssay Description:Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProteinase-activated receptor 2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM429536(US10550089, Example 10 | US10995072, Example 11)
Affinity DataIC50: >7.70E+4nMAssay Description:Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProteinase-activated receptor 2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM429536(US10550089, Example 10 | US10995072, Example 11)
Affinity DataIC50:  5.90E+3nMAssay Description:Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProteinase-activated receptor 2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM429536(US10550089, Example 10 | US10995072, Example 11)
Affinity DataIC50: >4.10E+4nMAssay Description:Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProteinase-activated receptor 2(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM429536(US10550089, Example 10 | US10995072, Example 11)
Affinity DataIC50:  1.66E+3nMAssay Description:Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent