BDBM429997 2-({4-[N-(3-cyano-4- fluorophenyl)-N'- hydroxycarbamimidoyl]-1,2,5- oxadiazol-3-yl}sulfanyl)-N- oxetan-3-ylacetamide::US10538497, Example 186

SMILES O\N=C(/Nc1ccc(F)c(c1)C#N)c1nonc1SCC(=O)NC1COC1

InChI Key InChIKey=JVBTTXBYZNCRCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429997   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM429997(US10538497, Example 186 | 2-({4-[N-(3-cyano-4- flu...)
Affinity DataIC50: 180nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 uM delta aminolevulin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent