BDBM430006 N-(3-bromo-4-fluorophenyl)-4- ((2-((3S,4S)-3,4- dihydroxypiperidin-1-yl)-2- oxoethyl)thio)-N'-hydroxy-1,2,5- oxadiazole-3-carboximidamide::US10538497, Example 196

SMILES O\N=C(/Nc1ccc(F)c(Br)c1)c1nonc1SCC(=O)N1CC[C@H](O)[C@@H](O)C1

InChI Key InChIKey=UBMDTDHYEKPAJA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430006   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM430006(US10538497, Example 196 | N-(3-bromo-4-fluoropheny...)
Affinity DataIC50: 62.3nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 uM delta aminolevulin...More data for this Ligand-Target Pair
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Date in BDB:
11/9/2020
Entry Details
US Patent