BDBM432362 N-(1-((R)-3-((S)-2-aminopropanamido)-2- (4-hydroxy-3- iodobenzyl)propanoyl)piperidin-4-yl)-5- cyclopropylisoxazole-3-carboxamide::US10577363, Compound 61

SMILES C[C@H](N)C(=O)NC[C@@H](Cc1ccc(O)c(I)c1)C(=O)N1CCC(CC1)NCc1cc(on1)C1CC1

InChI Key InChIKey=XOPGEMMFXPFIOM-MAUKXSAKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 432362   

TargetHistone-lysine N-methyltransferase SMYD3(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM432362(N-(1-((R)-3-((S)-2-aminopropanamido)-2- (4-hydroxy...)
Affinity DataIC50:  1.53E+4nMAssay Description:The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent