BDBM432426 5-cyclopropyl-N-(9-(2-(piperidin-4- yl)acetyl)-9-azabicyclo[3.3.1]nonan-3- yl)isoxazole-3-carboxamide::US10577363, Compound 125

SMILES O=C(CC1CCNCC1)N1C2CCCC1CC(C2)NC(=O)c1cc(on1)C1CC1

InChI Key InChIKey=HSOSPRMUWWAQQT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 432426   

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM432426(US10577363, Compound 125 | 5-cyclopropyl-N-(9-(2-(...)
Affinity DataIC50: 7.76E+3nMAssay Description:The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent