BDBM432531 US10577363, Compound 231::ethyl 2-(((2S,4S)-4-(5- cyclopropylisoxazole-3-carboxamido)-2- methylpiperidin-1-yl)sulfonyl)acetate

SMILES CCOC(=O)CS(=O)(=O)N1CC[C@@H](C[C@@H]1C)NC(=O)c1cc(on1)C1CC1

InChI Key InChIKey=DHQPDPGQDCDYGK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 432531   

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM432531(ethyl 2-(((2S,4S)-4-(5- cyclopropylisoxazole-3-car...)
Affinity DataIC50: 1.17E+3nMAssay Description:The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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