BDBM432545 US10577363, Compound 245::ethyl 2-(((2S,4R)-4-(5- cyclopropylisoxazole-3-carboxamido)-2- methylpiperidin-1-yl)sulfonyl)acetate

SMILES CCOC(=O)CS(=O)(=O)N1CC[C@H](C[C@@H]1C)NC(=O)c1cc(on1)C1CC1

InChI Key InChIKey=DHQPDPGQDCDYGK-WCQYABFASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 432545   

TargetHistone-lysine N-methyltransferase SMYD3(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM432545(US10577363, Compound 245 | ethyl 2-(((2S,4R)-4-(5-...)
Affinity DataIC50: >1.00E+4nMAssay Description:The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent