BDBM433004 N-((2S,4S)-2-benzyl-1-(((1-(3- hydroxypropyl)piperidin-4- yl)methyl)sulfonyl)piperidin-4-yl)-5- cyclopropylisoxazole-3-carboxamide::US10577363, Compound 707

SMILES OCCCN1CCC(CS(=O)(=O)N2CC[C@@H](C[C@@H]2Cc2ccccc2)NC(=O)c2cc(on2)C2CC2)CC1

InChI Key InChIKey=UZVDRQKGPPKOJH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433004   

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM433004(US10577363, Compound 707 | N-((2S,4S)-2-benzyl-1-(...)
Affinity DataIC50: 247nMAssay Description:The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent