BDBM433380 1-(6-(3-(6-methylpyridin-2- yl)imidazo[1,5-a]pyridin-6- yl)pyridin-2-yl)propan-1- amine::US10577367, Example 275

SMILES CCC(N)c1cccc(n1)-c1ccc2cnc(-c3cccc(C)n3)n2c1

InChI Key InChIKey=JYGCYOPZDYZSLJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433380   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM433380(US10577367, Example 275 | 1-(6-(3-(6-methylpyridin...)
Affinity DataIC50: 100nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2020
Entry Details
US Patent