BDBM433390 US10562850, Compound 22b::US11066360, Compound 22b

SMILES Cc1ccc(NC(=O)N2C[C@H](O)C[C@@H]2C(=O)Nc2cc(ccc2F)C(N)(CCC2CC2)c2cccc(c2)C#N)cc1

InChI Key InChIKey=IWZUFFQUBYJSIV-IYGDAUFUSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 433390   

TargetPlasma kallikrein(Homo sapiens (Human))
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM433390(US10562850, Compound 22b | US11066360, Compound 22...)
Affinity DataKi: >100nMAssay Description:The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates (DiaPharma Group, Inc., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Biocryst Pharmaceuticals

US Patent
LigandPNGBDBM433390(US10562850, Compound 22b | US11066360, Compound 22...)
Affinity DataKi: >100nMAssay Description:The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates. In these experiments, 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent