BDBM433799 US10562878, Compound 199

SMILES CN(C)CC1(CCCC(C)(O)C1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=BOVIUBFVSXFRBB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 433799   

TargetSodium-dependent serotonin transporter(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433799(US10562878, Compound 199)
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetNeuroepithelial cell-transforming gene 1 protein(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433799(US10562878, Compound 199)
Affinity DataIC50: 2.59E+3nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM433799(US10562878, Compound 199)
Affinity DataIC50: 462nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent