BDBM434484 US10562891, Example 398::US11008308, Example 398

SMILES CCC(=O)N1CCC(COc2cc(F)c3c(c2)nc(CSC2CCOCC2)[nH]c3=O)CC1

InChI Key InChIKey=LUFFVXYCVIGQRO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 434484   

TargetProtein mono-ADP-ribosyltransferase PARP14 [1611-1801](Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM434484(US10562891, Example 398 | US11008308, Example 398)
Affinity DataIC50: 1.00E+3nMAssay Description:Enzymatic inhibition of PARP14 was measured using a dissociation-enhanced lanthanide fluorescence immunoassay (DELFIA) monitoring the auto-modificati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM434484(US10562891, Example 398 | US11008308, Example 398)
Affinity DataIC50: 1.00E+3nMAssay Description:Enzymatic inhibition of PARP14 was measured using a dissociation-enhanced lanthanide fluorescence immunoassay (DELFIA) monitoring the auto-modificati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2021
Entry Details
Go to US Patent