BDBM435291 US10568876, Example 54::methyl 3-(2-((1-methylcyclopropyl) carbamoyl)-8-(((trans)-2- phenylcyclopropanecarboxamido)methyl)- 1,2,3,4-tetrahydroisoquinolin-5-yl) benzoate (mixture of 2 isomers)

SMILES COC(=O)c1cccc(c1)-c1ccc(CNC(=O)[C@H]2C[C@@H]2c2ccccc2)c2CN(CCc12)C(=O)NC1(C)CC1

InChI Key InChIKey=BVAXFAYLRPXJTB-IZLXSDGUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435291   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM435291(US10568876, Example 54 | methyl 3-(2-((1-methylcyc...)
Affinity DataIC50:  1.13nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent