BDBM435366 US10568876, Example 126::methyl 3-(2-(3-methoxypropanoyl)-8-((2- phenylcyclopropanecarboxamido)methyl)- 1,2,3,4-tetrahydroisoquinolin-5- yl)benzoate (mixture of 4 isomers)

SMILES COCCC(=O)N1CCc2c(C1)c(CNC(=O)C1CC1c1ccccc1)ccc2-c1cccc(c1)C(=O)OC

InChI Key InChIKey=HOIDEHIBJSZCEQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435366   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM435366(US10568876, Example 126 | methyl 3-(2-(3-methoxypr...)
Affinity DataIC50:  1.77E+3nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent