BDBM435423 US10570116, Compound C31

SMILES CN(CCc1nc2ccccc2c(=O)[nH]1)C(=O)N1CCC(C(=O)c2cnn(C)c2)CC1

InChI Key InChIKey=PEOXTCZVHIZAKJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 435423   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 435423BDBM435423(US10570116, Compound C31)
Affinity DataIC50: 2.20nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 435423BDBM435423(US10570116, Compound C31)
Affinity DataIC50: 3nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 435423BDBM435423(US10570116, Compound C31)
Affinity DataIC50: 5.30E+3nMAssay Description:PARP-1: The autoparsylation assay is performed as 384-well HTRF (Cisbio, Codolet, France) assay format in Greiner low volume nb 384-well microtiter p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent