BDBM435788 Methyl 2-methyl-3-(2-oxo-1,3-dihydrobenzimidazol-5-yl)benzoate;::US10611730, Example 46

SMILES COC(=O)c1cccc(c1C)-c1ccc2[nH]c(=O)[nH]c2c1

InChI Key InChIKey=CNKCLQDWRZSXOY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435788   

TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435788(Methyl 2-methyl-3-(2-oxo-1,3-dihydrobenzimidazol-5...)
Affinity DataIC50:  50.1nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent