BDBM435790 Methyl 2-methoxy-3-(2-oxo-1,3-dihydrobenzimidazol-5-yl)benzoate;::US10611730, Example 48

SMILES COC(=O)c1cccc(-c2ccc3[nH]c(=O)[nH]c3c2)c1OC

InChI Key InChIKey=QGONBARYLQUQBE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435790   

TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435790(Methyl 2-methoxy-3-(2-oxo-1,3-dihydrobenzimidazol-...)
Affinity DataIC50:  6.31E+3nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent