BDBM436027 5-[2-Methyl-3-(1,2,4-oxadiazol-5-yl)phenyl]-1,3-dihydrobenzimidazol-2-one;::US10611730, Example 199

SMILES Cc1c(cccc1-c1ccc2[nH]c(=O)[nH]c2c1)-c1ncno1

InChI Key InChIKey=SVGUZCRTHOWOMY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436027   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436027(US10611730, Example 199 | 5-[2-Methyl-3-(1,2,4-oxa...)
Affinity DataIC50: 63.1nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent