BDBM436533 US10590140, Example 309::methyl 3-(2- (ethylamino)-9-methyl- 5-oxo-5,7,8,9- tetrahydro-6H- pyrimido[4,5- e][1,4]diazepin-6- yl)benzoate

SMILES CCNc1ncc2c(n1)N(C)CCN(c1cccc(c1)C(=O)OC)C2=O

InChI Key InChIKey=PCWWOMQJNYDVAJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436533   

TargetVoltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103](Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM436533(US10590140, Example 309 | methyl 3-(2- (ethylamino...)
Affinity DataKi:  300nMAssay Description:α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent