BDBM436622 (S)-9-ethyl-6-(4-(3- (methylamino)-1- (thiophen-2- yl)propoxy)benzyl)- 6,7,8,9-tetrahydro- 5H-pyrimido[4,5- e][1,4]diazepin-5-one::US10590140, Example 398

SMILES CCN1CCN(Cc2ccc(O[C@@H](CCNC)c3cccs3)cc2)C(=O)c2cncnc12

InChI Key InChIKey=TYSLOBOSJIJVFT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436622   

TargetVoltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103](Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM436622(US10590140, Example 398 | (S)-9-ethyl-6-(4-(3- (me...)
Affinity DataKi:  300nMAssay Description:α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent