BDBM436864 N-(3-Methyloxetan-3-yl)-2-[3-methyl-2-oxo-6-[3- (trifluoromethyl)phenyl]imidazo[4,5-b]pyridin-1-yl]acetamide::US10617676, Example 199::US11207298, Example 199

SMILES Cn1c2ncc(cc2n(CC(=O)NC2(C)COC2)c1=O)-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=CYYOXQGSASGHRV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 436864   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436864(US10617676, Example 199 | N-(3-Methyloxetan-3-yl)-...)
Affinity DataIC50: 2.66E+3nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436864(US10617676, Example 199 | N-(3-Methyloxetan-3-yl)-...)
Affinity DataIC50: 2.66E+3nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent