BDBM437282 3-(1-(4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-1H- pyrazol-1-yl)ethyl)benzonitrile::US10617680, Example 16::US11020380, Example 16

SMILES CC(c1cccc(c1)C#N)n1cc(cn1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=OEAAAARRDHHNPZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437282   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437282BDBM437282(3-(1-(4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-1...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437282BDBM437282(3-(1-(4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-1...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent