BDBM437339 (S)-N-(1-(5-(1-benzyl-1H-pyrazol-4-yl)-1-methyl-2-oxo-1,2- dihydropyridin-4-yl)pyrrolidin-3-yl)acetamide::US10617680, Example 73::US11020380, Example 73

SMILES CC(=O)N[C@H]1CCN(C1)c1cc(=O)n(C)cc1-c1cnn(Cc2ccccc2)c1

InChI Key InChIKey=OGBNEWXOTNOPGY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437339   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437339BDBM437339((S)-N-(1-(5-(1-benzyl-1H-pyrazol-4-yl)-1-methyl-2-...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437339BDBM437339((S)-N-(1-(5-(1-benzyl-1H-pyrazol-4-yl)-1-methyl-2-...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent