BDBM437348 1-(5-(1-benzyl-1H-pyrazol-4-yl)-1-methyl-2-oxo-1,2- dihydropyridin-4-yl)-N-isopropyl-1H-pyrrole-3-carboxamide::US10617680, Example 82::US11020380, Example 82

SMILES CC(C)NC(=O)c1ccn(c1)-c1cc(=O)n(C)cc1-c1cnn(Cc2ccccc2)c1

InChI Key InChIKey=XRLGXLSNLQPNQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437348   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437348BDBM437348(1-(5-(1-benzyl-1H-pyrazol-4-yl)-1-methyl-2-oxo-1,2...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437348BDBM437348(1-(5-(1-benzyl-1H-pyrazol-4-yl)-1-methyl-2-oxo-1,2...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent