BDBM437381 5-(1-benzyl-1H-pyrazol-4-yl)-1-methyl-4-(3-methyl-1H- pyrazol-5-yl)pyridin-2(1H)-one::US10617680, Example 115::US11020380, Example 115
SMILES Cc1cc(-c2cc(=O)n(C)cc2-c2cnn(Cc3ccccc3)c2)[nH]n1
InChI Key InChIKey=GJHVMZMWHMYURT-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 437381
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of BRD4 was determined as described previously. See, e.g., U.S. Pat. No. 9,034,900.More data for this Ligand-Target Pair