BDBM437397 5'-(1-benzyl-1H-pyrazol-4-yl)-1'-methyl- [2,4'-bipyridin]-2'(1'H)--one::US10617680, Example 131::US11020380, Example 131

SMILES Cn1cc(-c2cnn(Cc3ccccc3)c2)c(cc1=O)-c1ccccn1

InChI Key InChIKey=AGOBCKMKTJPDOS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437397   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437397BDBM437397(5'-(1-benzyl-1H-pyrazol-4-yl)-1'-methyl- [2,4'-bip...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437397BDBM437397(5'-(1-benzyl-1H-pyrazol-4-yl)-1'-methyl- [2,4'-bip...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent