BDBM437430 5-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-4- phenylpyridin-2(1H)-one::US10617680, Example 164::US11020380, Example 164

SMILES Cc1c(cnn1C)-c1cn(C)c(=O)cc1-c1ccccc1

InChI Key InChIKey=PCOUWPYKDXHIJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437430   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437430BDBM437430(5-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-4- pheny...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437430BDBM437430(5-(1,5-dimethyl-1H-pyrazol-4-yl)-1-methyl-4- pheny...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent