BDBM437460 5'-(1-Benzyl-1H-pyrazol-4-yl)-1'-methyl-1H,1'H- [3,4']bipyridinyl-6,2'-dione::US10617680, Example 194::US11020380, Example 194

SMILES Cn1cc(-c2cnn(Cc3ccccc3)c2)c(-c2ccc(=O)[nH]c2)cc1=O

InChI Key InChIKey=XQHFNACDLCAUNB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437460   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437460BDBM437460(5'-(1-Benzyl-1H-pyrazol-4-yl)-1'-methyl-1H,1'H- [3...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437460BDBM437460(5'-(1-Benzyl-1H-pyrazol-4-yl)-1'-methyl-1H,1'H- [3...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent