BDBM437463 3-Cyclopropyl-1-methyl-5-[1-(1-phenyl-ethyl)-1H- pyrazol-4-yl]-1H-pyridin-2-one::US10617680, Example 197::US11020380, Example 197

SMILES CC(c1ccccc1)n1cc(cn1)-c1cc(C2CC2)c(=O)n(C)c1

InChI Key InChIKey=UGCNMJAMBOSYGK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437463   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437463BDBM437463(3-Cyclopropyl-1-methyl-5-[1-(1-phenyl-ethyl)-1H- p...)
Affinity DataIC50: 5.00E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437463BDBM437463(3-Cyclopropyl-1-methyl-5-[1-(1-phenyl-ethyl)-1H- p...)
Affinity DataIC50: 5.00E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent