BDBM437526 4-Methoxy-2-[4-(1'-methyl-6,6'-dioxo-1,6,1',6'-tetrahydro- [3,4']bipyridinyl-3'-yl)-pyrazol-1-yl]-benzonitrile::US10617680, Example 260

SMILES COc1ccc(C#N)c(-n2cc(-c3cn(C)c(=O)cc3-c3ccc(=O)[nH]c3)cn2)c1

InChI Key InChIKey=UGPBTRZXDWZHBA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437526   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437526BDBM437526(4-Methoxy-2-[4-(1'-methyl-6,6'-dioxo-1,6,1',6'-tet...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent