BDBM437542 2-Chloro-6-[4-(1,1''-dimethyl-6,2''-dioxo-1,6,1'',2''- tetrahydro-[4,4'']bipyridinyl-3-yl)-pyrazol-1-yl]- benzonitrile::BDBM499588::US10617680, Example 276

SMILES Cn1ccc(cc1=O)-c1cc(=O)n(C)cc1-c1cnn(c1)-c1cccc(Cl)c1C#N

InChI Key InChIKey=DAWYEIUKGAWGOH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437542   

TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437542(2-Chloro-6-[4-(1,1''-dimethyl-6,2''-dioxo-1,6,1'',...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437542(2-Chloro-6-[4-(1,1''-dimethyl-6,2''-dioxo-1,6,1'',...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent