BDBM437563 5-(1-(2-(1H-tetrazol-5-yl)phenyl)-1H-pyrazol-4-yl)-4-(4- chlorophenyl)-1-methylpyridin-2(1H)-one::US10617680, Example 297::US11020380, Example 297

SMILES Cn1cc(-c2cnn(-c3ccccc3-c3nnn[nH]3)c2)c(-c2ccc(Cl)cc2)cc1=O

InChI Key InChIKey=BISKCBBDIBKLKN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437563   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437563BDBM437563(5-(1-(2-(1H-tetrazol-5-yl)phenyl)-1H-pyrazol-4-yl)...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437563BDBM437563(5-(1-(2-(1H-tetrazol-5-yl)phenyl)-1H-pyrazol-4-yl)...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent