BDBM437576 1,1'-dimethyl-5-(1-(1-phenylethyl)-1H-pyrazol-4-yl)-[4,4'- bipyridine]-2,2'(1H,1'H)-dione::US10617680, Example 310::US11020380, Example 310

SMILES CC(c1ccccc1)n1cc(cn1)-c1cn(C)c(=O)cc1-c1ccn(C)c(=O)c1

InChI Key InChIKey=IXYZKXYBKXQHHP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437576   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437576BDBM437576(1,1'-dimethyl-5-(1-(1-phenylethyl)-1H-pyrazol-4-yl...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437576BDBM437576(1,1'-dimethyl-5-(1-(1-phenylethyl)-1H-pyrazol-4-yl...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent