BDBM437579 6-(3-(dimethylamino)propoxy)-1'-methyl-5'-(1-(1- phenylethyl)-1H-pyrazol-4-yl)-[3,4'-bipyridin]-2'(1'H)-one::US10617680, Example 313

SMILES CC(c1ccccc1)n1cc(cn1)-c1cn(C)c(=O)cc1-c1ccc(OCCCN(C)C)nc1

InChI Key InChIKey=PEVYMWIDKRAPNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437579   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437579BDBM437579(6-(3-(dimethylamino)propoxy)-1'-methyl-5'-(1-(1- p...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent