BDBM437612 2-(4-{6-[(cyclopropylmethyl)amino]-1'-methyl-6'-oxo- 1',6'-dihydro-[3,4'-bipyridine]-3'-yl}-1H-pyrazol-1-yl)-6- fluorobenzonitrile::US10617680, Example 346::US11020380, Example 346

SMILES Cn1cc(-c2cnn(c2)-c2cccc(F)c2C#N)c(cc1=O)-c1ccc(NCC2CC2)nc1

InChI Key InChIKey=ZCYMIVMSGILCCD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437612   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437612BDBM437612(2-(4-{6-[(cyclopropylmethyl)amino]-1'-methyl-6'-ox...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437612BDBM437612(2-(4-{6-[(cyclopropylmethyl)amino]-1'-methyl-6'-ox...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent