BDBM437616 2-fluoro-6-[4-[1-methyl-6-oxo-4-(6-pyrrolidin-1-yl)-3- pyridyl)-3-pyridyl]pyrazol-1-yl]benzonitrile::US10617680, Example 350::US11020380, Example 350

SMILES Cn1cc(-c2cnn(c2)-c2cccc(F)c2C#N)c(cc1=O)-c1ccc(nc1)N1CCCC1

InChI Key InChIKey=QCFBXFJSAUTGBX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437616   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437616BDBM437616(2-fluoro-6-[4-[1-methyl-6-oxo-4-(6-pyrrolidin-1-yl...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437616BDBM437616(2-fluoro-6-[4-[1-methyl-6-oxo-4-(6-pyrrolidin-1-yl...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent