BDBM437659 5-(5-Acetyl-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazin-3- yl)-4-ethoxy-1-methyl-1H-pyridin-2-one::US10617680, Example 393::US11020380, Example 393

SMILES CCOc1cc(=O)n(C)cc1-c1cnn2CCN(Cc12)C(C)=O

InChI Key InChIKey=XTCDLAYUPZQBHP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437659   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437659BDBM437659(5-(5-Acetyl-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyra...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437659BDBM437659(5-(5-Acetyl-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyra...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent