BDBM437660 1-methyl-4-phenyl-5-(5-phenyloxazol-2-yl)pyridin-2(1H)- one::US10617680, Example 394::US10617680, Example 397::US11020380, Example 397

SMILES Cn1cc(-c2cnc(o2)-c2ccccc2)c(cc1=O)-c1ccccc1

InChI Key InChIKey=YBTINYLTXXXTAF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 437660   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437660BDBM437660(US10617680, Example 397 | 1-methyl-4-phenyl-5-(5-p...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437660BDBM437660(US10617680, Example 397 | 1-methyl-4-phenyl-5-(5-p...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437660BDBM437660(US10617680, Example 397 | 1-methyl-4-phenyl-5-(5-p...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent