BDBM438043 US10597366, Compound 298

SMILES C[C@]1(F)Cc2c([C@@H]1O)c(ccc2Oc1cc(F)cc(c1)C#N)S(C)(=O)=O

InChI Key InChIKey=QMHSDIULNLOSIY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 438043   

TargetEndothelial PAS domain-containing protein 1(Human)
Peloton Therapeutics

US Patent
LigandPNGBDBM438043(US10597366, Compound 298)
Affinity DataIC50: 1.61E+4nMAssay Description:HIF-2a: The total assay volume was about 100 uL in the following configuration: 2 uL compound in 100% DMSO, 88 uL buffer with protein and probe and 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent